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Knudsen-HCI Research

Wei Zhang, Mei Yee Koh, Deepika Sirohi, Jian Ying, Ben J. Brintz, Beatrice S. Knudsen
J Pathol Inform. 2023; 14: 100196

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Graphical Abstract

ONECUT2 AND CELL PLASTICITY IN PROSTATE CANCER

Racial disparities in ONECUT2 – KAISO interactions with clinical significance 
Collaborator: Michael R. Freeman -  Cedars Sinai Medical Center

Sophia Akinbo Masters student in the Master of Science in Laboratory Medicine and Biomedical Science Program  
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Nature Medicine 2018 - ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the
androgen axis


bioRiv 2023 - ONECUT2 Activates Diverse Resistance Drivers of Androgen Receptor-Independent Heterogeneity in Prostate Cancer
 

CHROMOSOMAL INSTABILITY & DNA DAMAGE REPAIR IN PROSTATE CANCER

Collaborator: Anne Cress – University of Arizona

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Collaborators at University of Utah

Allison Payne Laboratory

Thermal ablation of breast cancer

Kathie Ullman Laboratory

Mitotic checkpoint & nuclear membrane

Michelle Mendoza Lab

Mechanisms of cancer invasion

Melissa Reeves Laboratory

Tumor immune cell microenvironment